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Year Number of Results
1959 1
1963 4
1964 2
1965 2
1966 8
1967 7
1968 14
1969 10
1970 11
1971 19
1972 22
1973 22
1974 19
1975 105
1976 105
1977 96
1978 120
1979 140
1980 133
1981 197
1982 186
1983 239
1984 275
1985 292
1986 286
1987 320
1988 347
1989 386
1990 383
1991 450
1992 441
1993 393
1994 445
1995 414
1996 453
1997 504
1998 541
1999 516
2000 660
2001 750
2002 750
2003 778
2004 964
2005 1191
2006 1417
2007 1517
2008 1531
2009 1425
2010 1641
2011 1883
2012 1916
2013 1945
2014 1895
2015 1915
2016 1680
2017 1648
2018 1636
2019 1578
2020 1548
2021 1446
2022 1413
2023 1313
2024 601

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38,428 results

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Page 1
Extreme scale-down approaches for rapid chromatography column design and scale-up during bioprocess development.
Chhatre S. Chhatre S. Adv Biochem Eng Biotechnol. 2013;132:109-35. doi: 10.1007/10_2012_174. Adv Biochem Eng Biotechnol. 2013. PMID: 23307294 Review.
Chromatography is a ubiquitous protein purification step owing to its unparalleled ability to recover and purify molecules from highly complex industrial feedstocks. Traditionally, column development has been driven by a combination of prior experience and em …
Chromatography is a ubiquitous protein purification step owing to its unparalleled ability to recover and purify molecules from highl …
Development of a particle packed bed model for homogeneity evaluation of liquid chromatography column.
Kubo T, Ichikawa M, Adachi T, Watabe Y, Naito T, Otuka K. Kubo T, et al. J Chromatogr A. 2023 Aug 30;1705:464171. doi: 10.1016/j.chroma.2023.464171. Epub 2023 Jun 21. J Chromatogr A. 2023. PMID: 37385150
Particle packed columns used for liquid chromatography (LC) can suppress a column internal band broadening (hereinafter referred to as band broadening) by packing monodisperse particles homogenously. ...At first, microfluid LC columns was prepared usin …
Particle packed columns used for liquid chromatography (LC) can suppress a column internal band broadening (hereinafter …
In Silico Method Development of Achiral and Chiral Tandem Column Reversed-phase Liquid Chromatography for Multicomponent Pharmaceutical Mixtures.
Haidar Ahmad IA, Kiffer A, Barrientos RC, Losacco GL, Singh A, Shchurik V, Wang H, Mangion I, Regalado EL. Haidar Ahmad IA, et al. Anal Chem. 2022 Mar 8;94(9):4065-4071. doi: 10.1021/acs.analchem.1c05551. Epub 2022 Feb 24. Anal Chem. 2022. PMID: 35199987
Tandem column liquid chromatography (LC) is a convenient, cost-effective approach to resolve multicomponent mixtures by serially coupling columns on readily available one-dimensional separation systems without specialized user training. ...As a result, many …
Tandem column liquid chromatography (LC) is a convenient, cost-effective approach to resolve multicomponent mixtures by serial …
A guide of column selection for two-dimensional liquid chromatography method development of natural alkaloids.
Xu Y, Liu Y, Zhou H, Wang R, Yu D, Guo Z, Liang X. Xu Y, et al. Talanta. 2023 Jan 1;251:123738. doi: 10.1016/j.talanta.2022.123738. Epub 2022 Jul 21. Talanta. 2023. PMID: 35921743
Based on a comprehensive evaluation of applicability and orthogonality of several columns, this guide would provide a simple but clear starting point for column selection of 2D-LC method development. ...Detailed studies of peak shapes of every column w …
Based on a comprehensive evaluation of applicability and orthogonality of several columns, this guide would provide a simple but clea …
Column Characterization and Selection Systems in Reversed-Phase High-Performance Liquid Chromatography.
Žuvela P, Skoczylas M, Jay Liu J, Ba Czek T, Kaliszan R, Wong MW, Buszewski B, Héberger K. Žuvela P, et al. Chem Rev. 2019 Mar 27;119(6):3674-3729. doi: 10.1021/acs.chemrev.8b00246. Epub 2019 Jan 3. Chem Rev. 2019. PMID: 30604951 Review.
Often, two similar RP-HPLC columns are not equally suitable for the requisite separation, and to date, there is no universal RP-HPLC column covering a variety of analytes. This forces analytical laboratories to keep a multitude of diverse columns. Therefore, …
Often, two similar RP-HPLC columns are not equally suitable for the requisite separation, and to date, there is no universal RP-HPLC …
Column-to-column packing variation of disposable pre-packed columns for protein chromatography.
Schweiger S, Hinterberger S, Jungbauer A. Schweiger S, et al. J Chromatogr A. 2017 Dec 8;1527:70-79. doi: 10.1016/j.chroma.2017.10.059. Epub 2017 Oct 26. J Chromatogr A. 2017. PMID: 29089107 Free article.
While a full body of literature on these factors is available for HPLC columns, no comparable studies exist for preparative columns for protein chromatography. ...Since it was possible to determine differences in the column-to-column performance …
While a full body of literature on these factors is available for HPLC columns, no comparable studies exist for preparative column …
Development of tandem-column liquid chromatographic methods for pharmaceutical compounds using simulations based on hydrophobic subtraction model parameters.
Liu Z, Zhou Y, Wang Q, Foley JP, Stoll DR, Shackman JG. Liu Z, et al. J Chromatogr A. 2023 Apr 26;1695:463925. doi: 10.1016/j.chroma.2023.463925. Epub 2023 Mar 12. J Chromatogr A. 2023. PMID: 36965284
The liquid chromatography (LC) analysis of small molecule pharmaceutical compounds and related impurities is crucial in the development of new drug substances, but developing these separations is usually challenging due to analyte structural similarities. ... …
The liquid chromatography (LC) analysis of small molecule pharmaceutical compounds and related impurities is crucial in the develo …
Development of dual gradient column in liquid chromatography.
Oda T, Kitagawa S, Ohtani H. Oda T, et al. J Chromatogr A. 2006 Feb 10;1105(1-2):154-8. doi: 10.1016/j.chroma.2005.09.011. Epub 2005 Sep 23. J Chromatogr A. 2006. PMID: 16185701
The dual gradient column, in which both the chemical property of the stationary phase and the flow velocity in the mobile phase are heterogeneous longitudinally along the column, is developed to obtain the mobile phase gradient-like elution in an isocratic co …
The dual gradient column, in which both the chemical property of the stationary phase and the flow velocity in the mobile phase are h …
A review of two-dimensional liquid chromatography approaches using parallel column arrays in the second dimension.
Foster SW, Parker D, Kurre S, Boughton J, Stoll DR, Grinias JP. Foster SW, et al. Anal Chim Acta. 2022 Oct 2;1228:340300. doi: 10.1016/j.aca.2022.340300. Epub 2022 Aug 26. Anal Chim Acta. 2022. PMID: 36127000 Review.
Columns with different stationary phase chemistries can be used in the (2)D column array to increase complementarity by utilizing specific stationary phases for various first dimension fractions. More recently, this type of platform has been used to automate the …
Columns with different stationary phase chemistries can be used in the (2)D column array to increase complementarity by utiliz …
[Multi-column technologies in chromatographic analysis].
Wang X, Sun K, Zhang B. Wang X, et al. Se Pu. 2019 Feb 8;37(2):123-131. doi: 10.3724/SP.J.1123.2018.11023. Se Pu. 2019. PMID: 30693719 Review. Chinese.
In this review, we discussed the recent developments in multi-column chromatography and its applications in multidimensional separation, chip chromatography, capillary electrophoresis, stationary-phase screening, and serial column chromatogra …
In this review, we discussed the recent developments in multi-column chromatography and its applications in multidimens …
38,428 results
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